Various drug delivery systems are developed to deliver therapeutic and diagnostic agents to tissues covered with mucus, such as airways, nasal cavity, or oral cavity . However, the mucus, which present for protection of the tissues, significantly hinders the transport of these agents and ultimately mitigates their efficacy . Several studies have been performed to improve the transmucosal transport by studying the transport rates of polymeric nanoparticles with various sizes and surface chemistry [3–5]. However, drug delivery systems with improved transmucosal transport capability are still highly desired.
- Bioengineering Division
Enhanced Transmucosal Transport Using Osmolyte-Mediated Fluid-Matrix Interaction
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Teo, KY, Ibrahim, B, Park, S, Yoon, Y, & Han, B. "Enhanced Transmucosal Transport Using Osmolyte-Mediated Fluid-Matrix Interaction." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 37-38. ASME. https://doi.org/10.1115/SBC2011-53102
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