The equations of motion are derived for a system with inertial properties that are varying in time as a result of known relative motions between the rigid bodies comprising the system. This vector-dyadic formulation has been encoded into a computer program, making use of the conformal rotation vector for the representation of rotations. The numerical simulation of two different physical systems is presented in order to illustrate the dynamic effects of the changing inertial properties, and the usefulness of the encoded formulation for modeling these effects.

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