... manuscript posted December 22, 2012; published online February 7, 2013. Assoc. Editor: Michael Sacks. 04 09 2012 06 12 2012 While cryosurgery has proven capable in treating of a variety of conditions, it has met with some resistance among physicians, in part due to shortcomings...

... enhanced cryosurgery for a variety of disease conditions. Two important motivations for adjuvant use are: (1) increased control of the local disease in the area of freezing (i.e., reduced local recurrence of disease) and (2) reduced complications due to over-freezing into adjacent tissues (i.e., reduced...

...Daigo Tanaka; Kenji Shimada; Yoed Rabin Background : Cryosurgery is the destruction of undesired tissues by freezing, as in prostate cryosurgery, for example. Minimally invasive cryosurgery is currently performed by means of an array of cryoprobes, each in the shape of a long hypodermic needle...

...Jiayao Zhang; George A. Sandison; Jayathi Y. Murthy; Lisa X. Xu A comprehensive computational framework to simulate heat transfer during the freezing process in prostate cancer cryosurgery is presented. Tissues are treated as nonideal materials wherein phase transition occurs over a temperature...

...Nathan E. Hoffmann; John C. Bischof It has been hypothesized that vascular injury may be an important mechanism of cryosurgical destruction in addition to direct cellular destruction. In this study, we report correlation of tissue and vascular injury after cryosurgery to the temperature history...

...Nathan E. Hoffmann; John C. Bischof Current research in cryosurgery is concerned with finding a thermal history that will definitively destroy tissue. In this study, we measured and predicted the thermal history obtained during freezing and thawing in a cryosurgical model. This thermal history...