...-mail:  kyle.allen@bme.ufl.edu 11 10 2021 31 01 2022 09 03 2022 synovial fluid magnetic microparticles viscosity osteoarthritis National Institute of Arthritis and Musculoskeletal and Skin Diseases 10.13039/100000069 R01AR068424 Degradation of synovial fluid can...

...Eleftheria Michalaki; Zhanna Nepiyushchikh; Josephine M. Rudd; Fabrice C. Bernard; Anish Mukherjee; Jay M. McKinney; Thanh N. Doan; Nick J. Willett; J. Brandon Dixon The lymphatic system has been proposed to play a crucial role in preventing the development and progression of osteoarthritis (OA...

...Nolan M. Norton; Brandon Barnds; Terence E. McIff; E. Bruce Toby; Kenneth J. Fischer The basilar thumb joint is the joint second most commonly affected by osteoarthritis (OA) in the hand. Evaluation of dorsal subluxation of the thumb during a functional task such as key pinch could help assess OA...

...Chloe L. Chung; Denis J. DiAngelo; Douglas W. Powell; Max R. Paquette Patients who sustain irreversible cartilage damage or joint instability from ankle injuries are likely to develop ankle osteoarthritis (OA). A dynamic ankle orthosis (DAO) was recently designed with the intent to offload the foot...

.... This study investigated the feasibility of an EI concept for the treatment of early medial osteoarthritis (OA), which is an even more conservative treatment compared with traditional UKA. Unlike UKA components, the proposed design uses a reversed materials scheme consisting of a plastic inlay component...

...Yongnam Song; Dennis R. Carter; Nicholas J. Giori References [1] Roos , H. , Lauren , M. , Adalberth , T. , Roos , E. M. , Jonsson , K. , and Lohmander , L. S. , 1998 , “ Knee Osteoarthritis After Meniscectomy: Prevalence of Radiographic Changes After Twenty-One...

...., Osteoarthritis Initiative, which provides MR and other data for the knee, http://oai.epi-ucsf.org/datarelease/ , and the Musculoskeletal Research Laboratories dataset, which provides CT arthrography image data for the hip, http://mrl.sci.utah.edu/software/hip-image-data ). As an alternative to subject-specific...

...Jason W. Wheeler; Pete B. Shull; Thor F. Besier The external knee adduction moment (KAM) measured during gait is an indicator of tibiofemoral joint osteoarthritis progression and various strategies have been proposed to lower it. Gait retraining has been shown to be an effective, noninvasive...

...Christopher E. Henderson; Jill S. Higginson; Peter J. Barrance Knee osteoarthritis (OA) detrimentally impacts the lives of millions of older Americans through pain and decreased functional ability. Unfortunately, the pathomechanics and associated deviations from joint homeostasis that OA patients...

...Mack G. Gardner-Morse; Nelson J. Tacy; Bruce D. Beynnon; Maria L. Roemhildt Alterations to joint tissues, including subchondral bone, occur with osteoarthritis. A microindentation technique was developed to determine the local compressive modulus of subchondral bone. This test, in conjunction...

... the rate of progression of medial compartment knee osteoarthritis. The results of this study demonstrated that a subtle weight bearing shift to the medial side of the foot during walking produced with an active feedback system reduced the first peak of the knee adduction moment. While verbal instruction...

... biological tissues biomechanics boundary-elements methods cellular biophysics deformation elasticity encapsulation finite element analysis optimisation Young's modulus osteoarthritis collagen proteoglycan aggrecan numerical model inverse problem Mow , V. C. , Ratcliffe...

...Seungbum Koo, PhD; Nicholas J. Giori, MD; Garry E. Gold, MD; Chris O. Dyrby; Thomas P. Andriacchi, PhD Cartilage morphology change is an important biomarker for the progression of osteoarthritis. The purpose of this study was to assess the accuracy of in vivo cartilage thickness measurements from...

... diffusion photobleaching pericellular matrix articular cartilage FRAP collagen proteoglycan osteoarthritis Articular cartilage is the connective tissue that lines surfaces of bones in synovial joints. Cartilage disease, primarily in the form of osteoarthritis, is a major problem that affects...

... phenomenon. PG is nonuniformly distributed throughout the depth direction, and its amount or distribution may change in the degenerated articular cartilage such as osteoarthritis. In this paper, we used a 50 MHz ultrasound system to study the depth-dependent strain of articular cartilage under the osmotic...

...Li Cao; Inchan Youn; Farshid Guilak; Lori A Setton The mechanical properties of articular cartilage serve as important measures of tissue function or degeneration, and are known to change significantly with osteoarthritis. Interest in small animal and mouse models of osteoarthritis has increased...

... manuscript received May 2002. Associate Editor: T. C. Skalak. 01 July 1999 01 May 2002 30 09 2002 cellular biophysics biomechanics boundary-elements methods biological techniques physiological models boundary integral equations Cartilage Osteoarthritis Cell Mechanics...

... Division December 27, 1999; revised manuscript received February 6, 2000. Associate Technical Editor: R. Vanderby, Jr. 27 December 1999 06 February 2000 viscoelasticity physiological models cellular biophysics biorheology Cartilage Osteoarthritis Cell Mechanics Chondrocyte...