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Proceedings Papers

Finite Element Modeling of Osmotic Swelling in Tissue-Engineered Cartilage

Liming Bian, Terri Ann N. Kelly, Eric G. Lima, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 269-270, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192368
https://doi.org/10.1115/SBC2008-192368
View Paper titled, Finite Element Modeling of Osmotic Swelling in Tissue-Engineered Cartilage
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Topics: Biological tissues, Cartilage, Finite element analysis, Modeling, Bearings, Chondrocytes, Cracking (Materials), Fracture (Process), Hydrogels, Maintenance
Proceedings Papers

Effects of Joint Congruency on the Response of a Tension-Compression Nonlinear Constitutive Model for Cartilage

Benjamin J. Ellis, Gerard A. Ateshian, Andrew E. Anderson, Clare Canal, Steve A. Maas, Jeffrey A. Weiss
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1073-1074, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192897
https://doi.org/10.1115/SBC2008-192897
View Paper titled, Effects of Joint Congruency on the Response of a Tension-Compression Nonlinear Constitutive Model for Cartilage
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Topics: Cartilage, Compression, Constitutive equations, Tension, Anisotropy, Finite element analysis, Fluids, Materials properties, Stress
Proceedings Papers

Scaffold Properties Play a Critical Role in the Retention of Synthesized Glycosaminoglycans in Tissue Engineered Cartilage

Lindsay E. Kugler, Kenneth W. Ng, Christopher J. O’Conor, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1031-1032, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176558
https://doi.org/10.1115/SBC2007-176558
View Paper titled, Scaffold Properties Play a Critical Role in the Retention of Synthesized Glycosaminoglycans in Tissue Engineered Cartilage
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Topics: Biological tissues, Cartilage, Agar, Tissue engineering, Chondrocytes, Diffusion (Physics), Explosives, Maintenance, Physiology, Testing
Proceedings Papers

The Role of Microtubule Organization in Chondrocyte Response to Osmotic Loading

Elizabeth S. Oswald, Pen-hsiu Grace Chao, J. Chloe Bulinski, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 277-278, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176634
https://doi.org/10.1115/SBC2007-176634
View Paper titled, The Role of Microtubule Organization in Chondrocyte Response to Osmotic Loading
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Topics: Chondrocytes, Cartilage, Physiology, Signals
Proceedings Papers

Influence of Nutrient Channels on Development of Engineered Cartilage Properties

Liming Bian, Kenneth W. Ng, Eric G. Lima, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1055-1056, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176234
https://doi.org/10.1115/SBC2007-176234
View Paper titled, Influence of Nutrient Channels on Development of Engineered Cartilage Properties
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Topics: Agar, Cartilage, Chondrocytes, Diffusion (Physics), Dimensions, Materials properties, Mechanical properties
Proceedings Papers

Fickian Behavior and Concentration-Dependence of the Diffusion of Dextran in Agarose

Michael B. Albro, Vikram Rajan, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1061-1062, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176646
https://doi.org/10.1115/SBC2007-176646
View Paper titled, Fickian Behavior and Concentration-Dependence of the Diffusion of Dextran in Agarose
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Topics: Agar, Diffusion (Physics), Biological tissues, Cartilage, Chondrocytes, Dynamic testing (Materials), Fluorescence, Macromolecules, Mechanical properties, Soft tissues
Proceedings Papers

The Response of Tissue Engineered Cartilage to the Temporal Application of Transforming and Insulin-Like Growth Factors

Christopher J. O’Conor, Kenneth W. Ng, Lindsay E. Kugler, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1023-1024, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176523
https://doi.org/10.1115/SBC2007-176523
View Paper titled, The Response of Tissue Engineered Cartilage to the Temporal Application of Transforming and Insulin-Like Growth Factors
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Topics: Biological tissues, Cartilage, Tissue engineering, Agar, Biocompatibility, Chondrocytes, Mechanical properties
Proceedings Papers

Influence of Interleukin Treatment on Engineered and Native Articular Cartilage

Eric G. Lima, Liming Bian, Francis B. Gonzales, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 999-1000, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176220
https://doi.org/10.1115/SBC2007-176220
View Paper titled, Influence of Interleukin Treatment on Engineered and Native Articular Cartilage
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Topics: Cartilage, Biological tissues, Maintenance, Wounds
Proceedings Papers

The Role of Proteoglycans on Residual Stresses in the Aorta

Evren U. Azeloglu, Michael B. Albro, Vikrum A. Thimmappa, Charles R. Haggart, Kenneth W. Ng, Gerard A. Ateshian, Kevin D. Costa
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 219-220, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176566
https://doi.org/10.1115/SBC2007-176566
View Paper titled, The Role of Proteoglycans on Residual Stresses in the Aorta
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Topics: Aorta, Residual stresses, Biological tissues, Diseases, Stress
Proceedings Papers

Fabrication of Tissue-Engineered Cartilage Grafts With Anatomic Surface Contours for Repair of Large Focal Defects

Brendan L. Roach, Andrea R. Tan, Aaron M. Stoker, James L. Cook, Keith J. Yeager, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT38A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14657
https://doi.org/10.1115/SBC2013-14657
View Paper titled, Fabrication of Tissue-Engineered Cartilage Grafts With Anatomic Surface Contours for Repair of Large Focal Defects
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Topics: Biological tissues, Cartilage, Maintenance, Manufacturing, Surgery, Wounds
Proceedings Papers

Effects of Media Stirring and Presence of Nutrient Channels on Functional Properties of Large Engineered Cartilage Constructs

Alexander D. Cigan, Robert J. Nims, Michael B. Albro, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT39A001, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14128
https://doi.org/10.1115/SBC2013-14128
View Paper titled, Effects of Media Stirring and Presence of Nutrient Channels on Functional Properties of Large Engineered Cartilage Constructs
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Topics: Cartilage, Osteoarthritis, Tissue engineering, Young's modulus
Proceedings Papers

Prolonged Treatment of Ultra-Low Dose Chondroitinase ABC Improves Matrix Production in Engineered Cartilage

Grace D. O’Connell, Victoria Cui, Robert J. Nims, Adam B. Nover, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT39A002, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14191
https://doi.org/10.1115/SBC2013-14191
View Paper titled, Prolonged Treatment of Ultra-Low Dose Chondroitinase ABC Improves Matrix Production in Engineered Cartilage
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Topics: Cartilage, Stress, Bearings, Biological tissues, Equilibrium (Physics), Soft tissues
Proceedings Papers

Binding and Release Kinetics of Glycosaminoglycans and Collagen in Engineered Cartilage Under TGF-β Supplementation

Robert J. Nims, Alexander D. Cigan, Michael B. Albro, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT28A010, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14660
https://doi.org/10.1115/SBC2013-14660
View Paper titled, Binding and Release Kinetics of Glycosaminoglycans and Collagen in Engineered Cartilage Under TGF-β Supplementation
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Topics: Cartilage, Biological tissues, Chondrocytes, Mechanical properties, Osteoarthritis, Tissue engineering
Proceedings Papers

Chondroitinase-ABC Digestion and Dynamic Loading Increase Tension-Compression Nonlinearity in Tissue-Engineered Cartilage

Terri-Ann N. Kelly, Brendan L. Roach, Charles R. Mackenzie-Smith, Adam B. Nover, Eben G. Estell, Grace D. O’Connell, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT39A008, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14621
https://doi.org/10.1115/SBC2013-14621
View Paper titled, Chondroitinase-ABC Digestion and Dynamic Loading Increase Tension-Compression Nonlinearity in Tissue-Engineered Cartilage
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Topics: Biological tissues, Cartilage, Compression, Dynamic testing (Materials), Tension, Mechanical properties, Strength (Materials), Tensile strength, Young's modulus
Proceedings Papers

Glutaraldehyde Fixation of Bovine Humeral Head Articular Cartilage Maintains Functional Frictional Response

Brian K. Jones, Christopher S. Ahmad, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT55A008, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14216
https://doi.org/10.1115/SBC2013-14216
View Paper titled, Glutaraldehyde Fixation of Bovine Humeral Head Articular Cartilage Maintains Functional Frictional Response
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Topics: Cartilage, Friction, Arthroplasty, Bearings, Erosion, Fluid pressure, Lubrication, Metal surfaces, Pressure, Surgery
Proceedings Papers

Effects of Cartilage Constitutive Model on Specimen-Specific Validation and Predictions of Cartilage Mechanics in the Human Hip

Corinne R. Henak, Ashley L. Kapron, Andrew E. Anderson, Gerard A. Ateshian, Benjamin J. Ellis, Steve A. Maas, Jeffrey A. Weiss
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT47A003, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14132
https://doi.org/10.1115/SBC2013-14132
View Paper titled, Effects of Cartilage Constitutive Model on Specimen-Specific Validation and Predictions of Cartilage Mechanics in the Human Hip
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Topics: Cartilage, Constitutive equations, Reliability, Finite element analysis, Finite element model, Geometry, Osteoarthritis, Shear stress, Stress
Proceedings Papers

Removal of Sulfated Glycosaminoglycans Has a Differential Effect on Permeability of Bovine Articular Cartilage as Measured by Direct Permeation and Stress Relaxation

Heath B. Henninger, Clayton J. Underwood, Gerard A. Ateshian, Jeffrey A. Weiss
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 119-120, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206189
https://doi.org/10.1115/SBC2009-206189
View Paper titled, Removal of Sulfated Glycosaminoglycans Has a Differential Effect on Permeability of Bovine Articular Cartilage as Measured by Direct Permeation and Stress Relaxation
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Topics: Cartilage, Permeability, Relaxation (Physics), Stress, Fluids, Testing, Compression, Flow (Dynamics), Porous materials, Soft tissues
Proceedings Papers

Continuum Modeling of Biological Tissue Growth by Cell Division

Gerard A. Ateshian, Kevin D. Costa, Evren U. Azeloglu, Barclay Morrison, III, Clark T. Hung
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 143-144, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-205495
https://doi.org/10.1115/SBC2009-205495
View Paper titled, Continuum Modeling of Biological Tissue Growth by Cell Division
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Topics: Biological tissues, Modeling, Water, Accounting, Geometry
Proceedings Papers

Direct Validation of Active Solute Transport Induced by Dynamic Loading of Porous Hydrated Media

Michael B. Albro, Roland Li, Rajan E. Banerjee, Clark T. Hung, Gerard A. Ateshian
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 387-388, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206028
https://doi.org/10.1115/SBC2009-206028
View Paper titled, Direct Validation of Active Solute Transport Induced by Dynamic Loading of Porous Hydrated Media
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Topics: Dynamic testing (Materials), Agar, Biological tissues, Diffusion (Physics), Hydrogels, Cartilage, Desorption, Maintenance, Steady state
Proceedings Papers

Immediate and Long-Term Response of Engineered Cartilage After Mechanical Injury

Andrea R. Tan, Vikram Rajan, Gerard A. Ateshian, Clark T. Hung
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1273-1274, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204119
https://doi.org/10.1115/SBC2009-204119
View Paper titled, Immediate and Long-Term Response of Engineered Cartilage After Mechanical Injury
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Topics: Cartilage, Wounds, Biological tissues, Chondrocytes, Damage, Mechanical properties, Osteoarthritis, Stress, Young's modulus