Kuwait is a country with great potential for concentrated solar power (CSP) due to its high solar resource. The current work analyzes the potential of the application of CSP technology in the country and its particularities. Specifically, the current work examines a CSP plant with parabolic trough collector (PTC) technology and how this technology is affected in its performance depending on the location (inland or coastal) and the refrigeration system (wet, dry, or seawater cooled). The modeling methodology is based on a two-step approach: first, the Rankine steam power cycle is modeled in detail in a state-of-the-art steady-state simulation environment, obtaining the performance of the power cycle for each cooling technology; second, the power cycle performance maps are integrated into a detailed transient system-level simulation model of the complete CSP plant in order to perform annual yield simulations for the different representative locations of the climate of Kuwait. These results provide valuable information on both the potential of this technology for its more immediate application such as electricity generation and other future applications such as the desalination of seawater where the location must necessarily be coastal.