Biological tissues undergo complex phase change heat transfer processes during cryosurgery, and a theoretical model is preferable to forecast this heat experience. A mathematical model for phase change heat transfer in cryosurgery was established. In this model, a fractal treelike branched network was used to describe the complicated geometrical frame of blood vessels. The temperature distribution and ice crystal growth process in biological tissue including normal tissue and tumor embedded with two cryoprobes were numerically simulated. The effects of cooling rate, initial temperature, and distance of two cryoprobes on freezing process of tissue were also studied. The results show that the ice crystal grows more rapidly in the initial freezing stage (<600 s) and then slows down in the following process, and the precooling of cryoprobes has no obvious effect on freezing rate of tissue. It also can be seen that the distance of 10 mm between two cryoprobes produces an optimal freezing effect for the tumor size (20 mm × 10 mm) in the present study compared with the distances of 6 mm and 14 mm. The numerical results are significant in providing technical reference for application of cryosurgery in clinical medicine.
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September 2011
Research Papers
Three-Dimensional Numerical Study on Freezing Phase Change Heat Transfer in Biological Tissue Embedded With Two Cryoprobes
Fang Zhao,
Fang Zhao
School of Energy and Environment, IIUSE,
Southeast University
, Sipailou 2#, Nanjing, Jiangsu 210096, P. R. China
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Zhenqian Chen
Zhenqian Chen
School of Energy and Environment, IIUSE,
e-mail: zqchen@seu.edu.cn
Southeast University
, Sipailou 2#, Nanjing, Jiangsu 210096, P. R. China
Search for other works by this author on:
Fang Zhao
School of Energy and Environment, IIUSE,
Southeast University
, Sipailou 2#, Nanjing, Jiangsu 210096, P. R. China
Zhenqian Chen
School of Energy and Environment, IIUSE,
Southeast University
, Sipailou 2#, Nanjing, Jiangsu 210096, P. R. China
e-mail: zqchen@seu.edu.cn
J. Thermal Sci. Eng. Appl. Sep 2011, 3(3): 031007 (7 pages)
Published Online: August 12, 2011
Article history
Received:
December 19, 2010
Revised:
June 7, 2011
Online:
August 12, 2011
Published:
August 12, 2011
Citation
Zhao, F., and Chen, Z. (August 12, 2011). "Three-Dimensional Numerical Study on Freezing Phase Change Heat Transfer in Biological Tissue Embedded With Two Cryoprobes." ASME. J. Thermal Sci. Eng. Appl. September 2011; 3(3): 031007. https://doi.org/10.1115/1.4004425
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